As you age, your testosterone level might gradually decrease. Low testosterone levels affect your body by reducing body density, muscle mass, sperm count, and red blood cell production.
At this time, testosterone replacement therapy may look promising for you to eliminate such impacts. In this blog, we share more information about testosterone replacement therapy and how long it takes to observe its influence on the body; for testosterone replacement therapy check here.
What Is Testosterone Replacement Therapy (TRT)?
To treat reduced levels of testosterone, testosterone replacement therapy is the ultimate anti-aging formula which is available in different forms like injections, pellets, and gels.
The testosterone gel is applied directly, which gets absorbed into the skin. However, injections are injected into the muscles, and pellets are implanted in the soft tissues. It takes the body a few days for testosterone to get absorbed into the bloodstream.
Undoubtedly, there are positive as well as adverse effects of testosterone replacement therapy. Some positive results are improvement in mood, strength, and cognition. After getting the treatment, people are often curious about how long it takes to experience the positive effects. However, it depends on various factors.
Treatment type and dosage play a crucial role in determining the outcome. For example, an individual taking a 200 mg dose of intramuscular testosterone each week will see results faster than someone taking 100 mg.
However, it does not mean that a higher dosage is better to increase your testosterone levels as it further depends on the functioning of the body. It is hard to predict the time to see the outcome even if the two individuals take the same dose every week, mainly because of differences in everyone’s bodies.
The following is a standard timeline in which you could notice the effects of TRT.
Timeline For Sexual Interests
To increase libido and sexual function, many people do prefer testosterone replacement therapy. With TRT, sexual desire and erections are the common things to grow at the quickest speed.
Sometimes, people experience changes in a week, but most commonly, your sex life improves after three weeks and may take up to 6 weeks. In comparison, ejaculations can take up to 6 months to enhance.
Lipids And Insulin
TRT does have a positive influence on insulin sensitivity in the body. Fundamentally, if you are more sensitive to insulin, then you are healthier. However, the opposite can lead to health issues like high blood pressure or diabetes. People suffering from diabetes or pre-diabetes opt for TRT for a speedy recovery, which can significantly improve insulin sensitivity.
While the insulin sensitivity takes at least a week or two to improve, the glycemic control (rise in blood sugar) effects may appear after three months but can take up to a year.
Triglycerides (lipid) levels typically drop after three to four months, sometimes even for a year or longer. Furthermore, the total cholesterol levels do take one to three months to come down.
Body Composition
When you undergo TRT for a few months, it can change the body’s appearance by building tissue and putting on lean muscles. Also, testosterone plays a substantial part in obesity, glucose homeostasis, and lipid metabolism, and it is vital to maintain.
Within three to four months, you can notice muscle gains, modifications in fat mass, and lean body mass. However, it can also take six months to twelve months to stabilize.
Inflammation effects will happen in three to twelve weeks. Furthermore, the impact on the bones occurs at least six months after the treatment, and it lasts for three years or more.
Mental Health
The quality of life is affected within three to four weeks, and nevertheless, for supreme advantages, it may take more time. You can notice effects on depressive tempers after three to six weeks, and for full recovery, it may take up to 18-30 weeks.
The treatment also improves spatial working memory within three weeks, whereas after six weeks, further improvements can be seen.
Cardiovascular And Blood Pressure
With TRT, a decline in diastolic blood pressure can be seen in 3-9 months, while a drop in resting heart rates occurs after 40-44 weeks.
Some Other Effect On The Timeline
It takes about a year for prostate-specific antigen and volume to increase. However, the symptoms of erythropoiesis begin to appear after three months, peaking between nine and twelve months.
Time-course effects of testosterone show significant differences, which are mainly due to a variety of biological factors. The explanation mentioned above is based on various studies conducted by researchers over many years. It does give you an idea about the approximate span the therapy takes to show its results.

